Women in BioCop - Biographies
Organisation: National Institute for Public Health & the Environment
Country: Netherlands
* BA. Chemistry
Ms van den Top has 15 + years experience in analytical chemistry, focusing on natural toxins in food (mycotoxins, phycotoxins, plant toxins) and LC/MS methodology.
Other experience includes being actively involved in a number of EU projects listed below:
* EU FP3 project on the development of CRMs for paralytic shellfish poisoning toxins (see publications H.J. van den Top et al, Food Additives and Contaminants 17 (2000), 419- 433 and 18 (2001), 810- 824.)
* EU FP4 project on the Validation of Analytical Methods to Determine the Content of Aflatoxin, Ochratoxin and Patulin in Foodstuffs of Vegetable Origin.
* EU FP4 project, ZONMAIZE* EU FP5 project, DONCALIBRANT
* Working groups NRL for Marine BiotoxinsMs van den Top is actively involved in providing technical and scientific support in activities related to work package 5 and also the design, conduct and evaluation of method validation studies of methods developed within work packages 5 and 10.
Areas of interest:
mycotoxins, phycotoxins, plant toxins, and LC/MS
Languages:
Dutch, English, German
Publications:
1. H.P. van Egmond, A. Mouriño, P.A. Burdaspal, J. Bustos, T. Legarda, A. Mesego,W.E. Paulsch, C. Salgado, H.J. van den Top, A. Boenke. “The certification of the mass fractions of saxitoxin and dc-saxitoxin in two mussel reference materials (CRMs 542 & 543) including the identification of other PSP-toxins, and a spiking procedure based on an enrichment solution (CRM 663) with a certified mass concentration of saxitoxin” EUR report 18318 (1998), 124 pp. European Commission, Directorate-General Science, Research and Development, Brussels, Belgium.
2. H.J. van den Top, A. Boenke, P.A. Burdaspal, J. Bustos, H.P. van Egmond, T. Legarda, A. Mesego, A. Mouriño, W.E. Paulsch, C. Salgado. "The development of reference materials for paralytic shellfish poisoning toxins in lyophilized mussel, I: Interlaboratory studies of methods of analysis". Food Addit. Cont. 17 (2000), 419-433.
3. H.J. van den Top, A. Boenke, P.A. Burdaspal, J. Bustos, H.P. van Egmond, T. Legarda, A. Mesego, A.Mouriño, W.E. Paulsch, C. Salgado. "The development of reference materials for paralytic shellfish poisoning toxins in lyophilized mussel, II: Certification study". Food Addit. Cont. 18 (2001), 810-824.
4. H.P. van Egmond, K.M. Jonker, M.Poelman, P. Scherpenisse, A.Stern, P. Wezenbeek, A.A. Bergwerff, H.J. van den Top. “Proficiency studies on the determination of Paralytic Shellfish Poisoning toxins in shellfish in the Netherlands”. Food Addit. Cont. 21 (2004), 331-340.
5. T.T. Mensinga, A.J.A.M. Sips, C.J.M. Rompelberg, K. van Twillert, J. Meulenbelt, H.J. van den Top, H.P. van Egmond, “Potato glycoalkaloids and adverse effects in humans: an ascending dose study”. Regulatory Toxicology and Pharmacology 41 (2005), 66-72.